Magnetic Nanoparticle for Biomedicine Applications | | Author : Gang Liu | | Abstract | Full Text | Abstract :Magnetic Nanoparticles (MNPs) have been widely applied in the area of biomedicine in recent years due to their broad versatility, such as good biological compatibility, unique physicochemical properties and easy guidance by external magnetic fields. In this review, the recent progress in the synthesis and surface modification of MNPs, as well as their applications in biomedicine including bioseparation, molecular detection, drug delivery, hyperthermia and Magnetic Resonance Imaging (MRI) and etc., have been summarized. |
| Nanomedicine to Tumor by Enzymosomes | | Author : Basavaraj K Nanjwade | | Abstract | Full Text | Abstract :Usually the enzymes have played a role in enhancing prodrug activation for active targeting by an antibody. In routine practice the use of enzymes is a difficult task due to the loss of activity by their degradation, although they do not have a capacity of penetrating into biological membrane, such a task is handled by placing the enzymes in suitable location i.e., encapsulating an enzyme to the surface of the lipid vesicles or surface of liposomes are called enzymosomes, thus the covalent link of enzymes will minimize alterations of the activity of enzymes, enhances half-life and achieved enzyme activity at targeted site such as tumour cell. The review article includes preparation techniques, characterization and stability of liposomal enzymes drug delivery system. |
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